System shock 2 toxin a locations9/21/2023 ![]() ![]() ![]() What is the management of skin and soft-tissue infections (SSTIs) in the era of community-associated MRSA (CA-MRSA)? SSTIsįor a cutaneous abscess, incision and drainage is the primary treatment (A-II). Please note that specific recommendations on vancomycin dosing and monitoring are not discussed in the sections for each clinical syndrome but are collectively addressed in detail in Section VIII. The key recommendations are summarized below in the Executive Summary each topic is discussed in greater detail within the main body of the guidelines. ![]() Areas of controversy in which data are limited or conflicting and where additional research is needed are indicated throughout the document and are highlighted in the Research Gaps section. Each section of the guidelines begins with a specific clinical question and is followed by numbered recommendations and a summary of the most-relevant evidence in support of the recommendations. The guidelines do not discuss active surveillance testing or other MRSA infection–prevention strategies in health care settings, which are addressed in previously published guidelines. The guidelines address issues related to the use of vancomycin therapy in the treatment of MRSA infections, including dosing and monitoring, current limitations of susceptibility testing, and the use of alternate therapies for those patients with vancomycin treatment failure and infection due to strains with reduced susceptibility to vancomycin. The primary objective of these guidelines is to provide recommendations on the management of some of the most common clinical syndromes encountered by adult and pediatric clinicians who care for patients with MRSA infections. This document constitutes the first guidelines of the IDSA on the treatment of MRSA infections. MRSA is a significant cause of both health care–associated and community-associated infections. ![]()
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